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Investigation on the mechanism of ginsenoside Rg3 in treating murine primary mammary tumor

Hongbo TANG MD, Zirong YE MM, Yuping REN MD, Zhanyong ZHU MD, Yiping WU MD,

Frontiers of Medicine 2009, Volume 3, Issue 4,   Pages 421-425 doi: 10.1007/s11684-009-0078-6

Abstract: A murine primary mammary tumor model was established to investigate the treatment with ginsenosides Rg3The relationship between ginsenosides Rg3 and primary mammary tumor was explored.Ginsenoside Rg3 was employed for treatment.Ginsenoside Rg3 can play an antitumor role in primary mammary tumor model by inhibiting angiogenesis,

Keywords： ginsenoside Rg3     mammary tumor     mice    

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Fundamental influences of particles on stirred and unstirred venting processes of foaming systems

Henrik LEIMEISTER,Jörg STEINBACH

Frontiers of Chemical Science and Engineering 2014, Volume 8, Issue 2,   Pages 141-148 doi: 10.1007/s11705-014-1423-0

Abstract: Venting is the common safety measure to protect plant equipment against excessive overpressure. So far, scenarios in which particles were part of the system and should have been accounted for did ignore their presence; the scenarios were treated like a two-phase system. Current research shows that particles can have a major influence on the venting behaviour. Experimental results indicate that particles affect level swell and relief flow especially of foamy systems. Based on those results four different layers of influence of the particle have been identified and are presented in a first model. Based on this model recommendations for the development of new and more complex models are given.

Keywords： venting     multi-phase    

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Studies of fiber-matrix debonding

Navneet DRONAMRAJU,Johannes SOLASS,Jörg HILDEBRAND

Frontiers of Structural and Civil Engineering 2015, Volume 9, Issue 4,   Pages 448-456 doi: 10.1007/s11709-015-0316-8

Abstract: In this paper, the debonding of a single fiber-matrix system of carbon fiber reinforced composite (CFRP) AS4/Epson 828 material is studied using Cohesive Zone Model (CZM). The effect of parameters namely, maximum tangential contact stress, tangential slip distance and artificial damping coefficient on the debonding length at the interface of the fiber-matrix is analyzed. Contact elements used in the CZM are coupled based on a bilinear stress-strain curve. Load is applied on the matrix, tangential to the interface. Hence, debonding is observed primarily in Mode II. Wide range of values are considered to study the inter-dependency of the parameters and its effect on debonding length. Out of the three parameters mentioned, artificial damping coefficient and tangential slip distance significantly affect debonding length. A thorough investigation is recommended for case wise interface debonding analysis, to estimate the optimal parametric values while using CZM.

Keywords： single fibre     cohesive zone model     interface debonding     carbon fiber reinforced composite (CFRP)    

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Removal of P4, PH3 and H2S from Yellow Phosphoric Tail Gas by a Catalytic

Ning Ping,Hans-Jörg Bart,Wang Xueqian,Ma Liping,Chen Liang

Strategic Study of CAE 2005, Volume 7, Issue 6,   Pages 27-35

Abstract: proved to be effective catalysts in the catalytic oxidation process (COP) for H2S and PH33, total phosphorus＜ 5 mg/m3 was obtained by using the COP process.

Keywords： catalyst     catalytic oxidation     H2S     P4     PH3     fixed bed    

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The lethal dose test of Ginsenoside CK and Icraiin for sperm in vitro

Yu Hongliang,Chang Mingxiu,Cao Henghai,Bo Liwei,Yang Yongjun,Li Chongmin,Li Ming

Strategic Study of CAE 2015, Volume 17, Issue 6,   Pages 86-88

Abstract:

Objective：To investigate the effects of Ginsenoside CK(Gin CK),Icraiin(Icr) for sperm survive in vitroTo adjust the semen concentration is 1.0×107/mL by culture medium of F-10(F-10),To add respect Ginsenosideof I2 group was 41.31±17.49,F group was 47.50±19.85,G2 group was 55.75±24.93,I3Ranking them from less to more motality were E2 groups,F groups,I2 groups,G2 groups,I3 groups,G1 group

Keywords： Ginsenoside CK     Icraiin     sperm     lethal dose    

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Distinct immune escape and microenvironment between RG-like and pri-OPC-like glioma revealed by single-cell

Frontiers of Medicine doi: 10.1007/s11684-023-1017-7

Abstract: their classification into primitive oligodendrocyte precursor cell (pri-OPC)-like and radial glia (RGThe RG-like tumors exhibited wild-type isocitrate dehydrogenase and tended to carry EGFR mutationsPTPRZ1 and B cell-specific receptors IGLC2/IGKC were expressed in pri-OPC-like and RG-likeTheir expression was positively correlated with those of immune checkpoint genes (e.g., LGALS3) and poor survivals as validated by the increased expression of LGALS3 upon IGKC overexpression

Keywords： single-cell RNA-seq     glioma     radial glia     primitive oligodendrocyte precursor cell     immune escape    

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Impact of photocatalytic remediation of pollutants on urban air quality

GEORGE, Anne BEELDENS, Fotios BARMPAS, Jean-François DOUSSIN, Giuseppe MANGANELLI, Hartmut HERRMANN, Jörg

Frontiers of Environmental Science & Engineering 2016, Volume 10, Issue 5, doi: 10.1007/s11783-016-0834-1

Abstract: Air pollution remediation using photocatalytic construction materials was tested. NO and VOC uptake rates on different materials were measured in the laboratory. Effective NO and VOC abatement levels were tested under real conditions. Recommendations for implementation of photocatalytic materials are provided. In the recent years, photocatalytic self-cleaning and “depolluting” materials have been suggested as a remediation technology mainly for NO and aromatic VOCs in urban areas. A number of products incorporating the aforementioned technology have been made commercially available with the aim to improve urban air quality. These commercial products are based on the photocatalytic properties of a thin layer of TiO at the surface of the material (such as glass, pavement, etc.) or embedded in paints or concrete. The use of TiO photocatalysts as an emerging air pollution control technology has been reported in many locations worldwide. However, up to now, the effectiveness measured in situ and the expected positive impact on air quality of this relatively new technology has only been demonstrated in a limited manner. Assessing and demonstrating the effectiveness of these depolluting techniques in real scale applications aims to create a real added value, in terms of policy making (i.e., implementing air quality strategies) and economics (by providing a demonstration of the actual performance of a new technique).

Keywords： Photocatalysis     Air pollution     Depollution efficiency     NOx     VOC     Air quality abatement and management    

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Development of CO2 Selective Poly(Ethylene Oxide)-Based Membranes: From Laboratory to Pilot Plant Scale

Torsten Brinkmann,Jelena Lillepärg,Heiko Notzke,Jan Pohlmann,Sergey Shishatskiy,Jan Wind,Thorsten

Engineering 2017, Volume 3, Issue 4,   Pages 485-493 doi: 10.1016/J.ENG.2017.04.004

Abstract: The membrane shows excellent CO2 permeances of up to 4 m3(STP)·(m2<

Keywords： Gas permeation     Thin-film composite membrane     CO2 separation     Carbon capture and storage     Biogas processing     Membrane modules    

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Synthesis of copolymers of 3-acryloyloxymethyl-3′-methyloxetane and 3-(2-(2-(2-Methoxyethylenoxy)ethylenoxy)ethylenoxy)-3′-methyloxetane and their ionic conductivity properties

YE Lin, ZHAO Yumei, FENG Zengguo, BAI Ying, WU Feng

Frontiers of Chemical Science and Engineering 2007, Volume 1, Issue 4,   Pages 343-348 doi: 10.1007/s11705-007-0062-0

Abstract: An oxetane-derived monomer, 3-acryloyloxymethyl-3′-methyloxetane (AMO) was prepared from the reactionof 3-hydromethyl-3-methyloxetane with acryloyl chloride.The cationic ring-opening copolymerization of AMO with another oxetane-derived monomer, 3-(2-(2-(2-methoxyethylenoxy)ethylenoxy)ethylenoxy)-3′-methyloxetane (MEMO) was conducted in CHCl solution using BF3 ·OEt/1, 4-butanediol

Keywords： 4-butanediol     2-methoxyethylenoxy     consistent     oxetane-derived     copolymer    

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Heterologous expression of signal protein 14-3-3 in and the subsequent immune response in mice

ZHENG Meijuan, SHEN Jilong, LUO Qingli, XU Yuanhong

Frontiers of Medicine 2008, Volume 2, Issue 1,   Pages 95-99 doi: 10.1007/s11684-008-0017-y

Abstract: The Sj14-3-3 gene was amplified and subcloned into the expression vector pPICZ?The protein of rSj14-3-3 was prepared and purified and BALB/c mice were immunized which was followedThe Sj14-3-3 gene was expressed and secreted into the medium and its molecular weight was about 35000antibody and rSj14-3-3 had a promising immune reactivity.The recombinant Sj14-3-3 of eukaryotic expression in was successfully harvested.

Keywords： development     challenging     rSj14-3-3     resistance     cultural supernatant    

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FOXP3 and Its Cofactors as Targets of Immunotherapies Review

Yasuhiro Nagai,Lian Lam,Mark I. Greene,Hongtao Zhang

Engineering 2019, Volume 5, Issue 1,   Pages 115-121 doi: 10.1016/j.eng.2019.01.001

Abstract:

Forkhead box P3 (FOXP3) is a "master regulator" of regulatory T cells (Tregs), which areAs a consequence, the PTMs change the stability of FOXP3 and its capability to regulate gene expressionAlthough FOXP3 per se is not an ideal drug target, deacetylases, acetyltransferases, kinases, and other enzymes that regulate the PTMs of FOXP3 are potential targets to modulate FOXP3 and TregFOXP3" side effects must be considered when inhibitors to these enzymes are used.

Keywords： Treg     Forkhead box P3 (FOXP3)     Post-translational modification     Autoimmune     Cancer    

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Haploinsufficiency of Lipin3 leads to hypertriglyceridemia and obesity by disrupting the expression and

Frontiers of Medicine doi: 10.1007/s11684-023-1003-0

Abstract: However, little is known about the function of Lipin3 in triglyceride (TG) metabolism.Hence, we generated Lipin3 heterozygous knockout (Lipin3-heKO) mice and cultured primary hepatocytesto explore the pathophysiological roles of Lipin3 in TG metabolism.Our study suggested that Lipin3 was a novel disease-causing gene inducing obesity and HTG.We also established a relationship between Lipin3 and mitochondrial dysfunction.

Keywords： Lipin3     Lipin1     hypertriglyceridemia     obesity     mitochondrial dysfunction    

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A Review on the 3D Printing of Functional Structures for Medical Phantoms and Regenerated Tissue and

Kan Wang, Chia-Che Ho, Chuck Zhang, Ben Wang

Engineering 2017, Volume 3, Issue 5,   Pages 653-662 doi: 10.1016/J.ENG.2017.05.013

Abstract: With the rapid advancement of three-dimensional (3D) printing and 3D bioprinting technologies, many researchersThis paper reviews the applications of these 3D printing and 3D bioprinting technologies for the fabricationThis review specifically discusses the state of the art along with new developments and trends in 3Dmedical phantoms, radiologically relevant medical phantoms, and physiological medical phantoms) and 3D

Keywords： 3D printing     3D bioprinting     Medical phantom     Regenerated tissue/organ     Scaffold    

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Influence and related mechanism of Retn gene expression on glucose uptake in 3T3-L1 cells

LI Yahui, DONG Shiyuan, YU Chao, JIANG Yu, LI Huaixing, SUN Shuhan

Frontiers of Medicine 2007, Volume 1, Issue 3,   Pages 269-273 doi: 10.1007/s11684-007-0051-1

Abstract: investigate the influence and the related mechanism of the gene on glucose uptake and insulin resistance in 3T3Radioimmunoassay was used to determine glucose uptake in 3T3-L1 cells with different gene expressionreal-time RT-PCR analysis were used to determine the mRNA levels of several glucose transport proteins in 3T3and glycogen synthase kinase-3b (GSK-3)., GSK-3 and p38MAPK, increased with overexpression in 3T3-L1 cells.

Keywords： 3T3-L1     influence     resistance     receptor substrate-1     transport    

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Combustion and emissions of RP-3 jet fuel and diesel fuel in a single-cylinder diesel engine

Frontiers in Energy 2023, Volume 17, Issue 5,   Pages 664-677 doi: 10.1007/s11708-021-0787-3

Abstract: The combustion characteristics and emission behaviors of RP-3 jet fuel were studied and compared to commercialcrank angle (CA) after top dead center (ATDC)) were adjusted to evaluate the engine performances of RP-3In comparison to diesel fuel, RP-3 jet fuel shows a retarded heat release and lagged combustion phaseAs a result, RP-3 jet fuel features a longer ignition delay (ID) time, a shorter combustion durationCompared with diesel fuel, the nitrogen oxides (NOx) emissions of RP-3 jet fuel are

Keywords： RP-3 jet fuel     diesel     engine     combustion     emissions    

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Title Author Date Type Operation

Investigation on the mechanism of ginsenoside Rg3 in treating murine primary mammary tumor

Hongbo TANG MD, Zirong YE MM, Yuping REN MD, Zhanyong ZHU MD, Yiping WU MD,

Journal Article

Fundamental influences of particles on stirred and unstirred venting processes of foaming systems

Henrik LEIMEISTER,Jörg STEINBACH

Journal Article

Studies of fiber-matrix debonding

Navneet DRONAMRAJU,Johannes SOLASS,Jörg HILDEBRAND

Journal Article

Removal of P4, PH3 and H2S from Yellow Phosphoric Tail Gas by a Catalytic

Ning Ping,Hans-Jörg Bart,Wang Xueqian,Ma Liping,Chen Liang

Journal Article

The lethal dose test of Ginsenoside CK and Icraiin for sperm in vitro

Yu Hongliang,Chang Mingxiu,Cao Henghai,Bo Liwei,Yang Yongjun,Li Chongmin,Li Ming

Journal Article

Distinct immune escape and microenvironment between RG-like and pri-OPC-like glioma revealed by single-cell

Journal Article

Impact of photocatalytic remediation of pollutants on urban air quality

GEORGE, Anne BEELDENS, Fotios BARMPAS, Jean-François DOUSSIN, Giuseppe MANGANELLI, Hartmut HERRMANN, Jörg

Journal Article

Development of CO2 Selective Poly(Ethylene Oxide)-Based Membranes: From Laboratory to Pilot Plant Scale

Torsten Brinkmann,Jelena Lillepärg,Heiko Notzke,Jan Pohlmann,Sergey Shishatskiy,Jan Wind,Thorsten

Journal Article

Synthesis of copolymers of 3-acryloyloxymethyl-3′-methyloxetane and 3-(2-(2-(2-Methoxyethylenoxy)ethylenoxy)ethylenoxy)-3′-methyloxetane and their ionic conductivity properties

YE Lin, ZHAO Yumei, FENG Zengguo, BAI Ying, WU Feng

Journal Article

Heterologous expression of signal protein 14-3-3 in and the subsequent immune response in mice

ZHENG Meijuan, SHEN Jilong, LUO Qingli, XU Yuanhong

Journal Article

FOXP3 and Its Cofactors as Targets of Immunotherapies

Yasuhiro Nagai,Lian Lam,Mark I. Greene,Hongtao Zhang

Journal Article

Haploinsufficiency of Lipin3 leads to hypertriglyceridemia and obesity by disrupting the expression and

Journal Article

A Review on the 3D Printing of Functional Structures for Medical Phantoms and Regenerated Tissue and

Kan Wang, Chia-Che Ho, Chuck Zhang, Ben Wang

Journal Article

Influence and related mechanism of Retn gene expression on glucose uptake in 3T3-L1 cells

LI Yahui, DONG Shiyuan, YU Chao, JIANG Yu, LI Huaixing, SUN Shuhan

Journal Article

Combustion and emissions of RP-3 jet fuel and diesel fuel in a single-cylinder diesel engine

Journal Article